THIADIAZOLONE DERIVATIVE AND USE THEREOF

摘要

Disclosed is a compound represented by the general formula [I], a pharmaceutically acceptable salt thereof, or a solvate of the compound or the salt. The compound is excellent in selective TACE-inhibiting activity. Therefore, a pharmaceutical composition comprising the compound can be used as a pharmaceutical agent effective for the prevention or treatment of a disease associated with TNF-a such, as rheumatoid arthritis and inflammatory bowel disease (IBD). [I] wherein each symbol is as defined in the description.