COMPOSITIONS AND METHODS FOR ENHANCING AN ADJUVANT
摘要
Provided herein are compositions and methods for enhancing an adjuvant ef fect. The methods involve targeting an adjuvant to an antigen presenting cel l (APC) using a compound that binds to a cell surface marker of an APC. Such methods are useful for stimulating an immune response in an animal, such as a human. Also provided are compositions that target an antigen and an adjuv ant to an APC.
申请公布号
CA2663851(A1)
申请公布日期
2008.04.03
申请号
CA20072663851
申请日期
2007.09.24
申请人
STICHTING KATHOLIEKE UNIVERSITEIT;ALEXION PHARMACEUTICALS, INC.
发明人
TACKEN, PAUL J.;BOWDISH, KATHERINE S.;FIGDOR, CARL GUSTAV;KRETZ-ROMMEL, ANKE;FAAS MCKNIGHT, SUSAN