| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a hybridoma to produce an antibody to human IL-6R. <P>SOLUTION: There provided are a hybridoma to produce an antibody to IL-6R, e.g. a hybridoma deposited as FERM BP-2998, a reshaped human antibody containing human L chain C region having low immunogenicity to human IL-6R and human H chain C region, an L chain V region containing CDR of mouse monoclonal antibody to human IL-6R, an H chain V region of mouse monoclonal antibody to human IL-6R, and a chimera antibody. <P>COPYRIGHT: (C)2008,JPO&INPIT</p> |
