发明名称 |
USE OF SUBSTITUTED QUINOLINE DERIVATIVES FOR THE TREATMENT OF DRUG RESISTANT MYCOBACTERIAL DISEASES |
摘要 |
The present invention relates to the use of a substituted quinoline derivative for the preparation of a medicament for the treatment of an infection with a drug resistant Mycobacterium strain wherein the substituted quinoline derivative is a compound according to Formula (Ia) or Formula (Ib) the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the tautomeric forms thereof and the N-oxide forms thereof. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the above compounds and one or more other antimycobacterial agents. |
申请公布号 |
EP1753427(B1) |
申请公布日期 |
2008.04.02 |
申请号 |
EP20050743054 |
申请日期 |
2005.05.24 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
ANDRIES, KOENRAAD, JOZEF, LODEWIJK, MARCEL;VAN GESTEL, JOZEF, FRANS, ELISABETHA |
分类号 |
A61K31/47;A61P31/06 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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