发明名称 |
MODULATING RESPONSIVENESS TO STEROIDS |
摘要 |
The present invention makes it possible to enhance steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an effective to said patient amount of an oligonucleotide comprising the sequence TTCGT and having a total length of up to 100 nucleotides. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals. |
申请公布号 |
EP1904077(A1) |
申请公布日期 |
2008.04.02 |
申请号 |
EP20060748071 |
申请日期 |
2006.06.30 |
申请人 |
INDEX PHARMACEUTICALS AB |
发明人 |
SPIIK, ANN-KRISTIN;LOEFBERG, ROBERT;BANDHOLTZ, LISA, CHARLOTTA;VON STEIN, OLIVER;ZARGARI, AREZOU |
分类号 |
A61K31/7088;A61K31/712;A61K31/7125;A61K45/06;A61P29/00;C12N15/117 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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