发明名称 |
Pravastatin pharmaceutical formulations and methods of their use |
摘要 |
The present invention relates to formulations comprising a therapeutically effective amount of pravastatin, or a pharmaceutically acceptable salt thereof, and methods of their use. The present formulations and methods are designed to release little or no pravastatin in the stomach but release a therapeutic amount of pravastatin in the small intestine, thereby limiting systemic exposure of the body to pravastatin and maximizing hepatics-specific absorption of the drug. The formulations and methods of the present invention are particularly useful for treating and/or preventing conditions that are benefited by decreasing levels of lipids and/or cholesterol in the body.
|
申请公布号 |
EP1905431(A1) |
申请公布日期 |
2008.04.02 |
申请号 |
EP20070120930 |
申请日期 |
2003.01.10 |
申请人 |
CIRC PHARMA RESEARCH AND DEVELOPMENT LIMITED |
发明人 |
BUTLER, JACKIE;DEVANE, JOHN;STARK, PAUL |
分类号 |
A61K9/20;A61K9/22;A61K9/28;A61K31/22;A61K31/225;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P43/00 |
主分类号 |
A61K9/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|