A NANO-PARTICLE PROCESS OF TRICLOCARBAN

摘要

A method for preparing salicylic acid microparticles is provided to obtain fine salicylic acid particles having an increased effective surface area and showing increasing skin absorptivity. A method for preparing salicylic acid microparticles utilizes a supercritical fluid process in which a mixed solution containing salicylic acid dissolved in an organic solvent is sprayed to and contacted with a supercritical fluid to produce salicylic acid particles, and then a supercritical fluid is introduced thereto to remove the organic solvent. In the method, the organic solvent is used in an amount corresponding to a weight fraction of salicylic acid of 0.0001-0.50.