发明名称 |
Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies |
摘要 |
The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/or signaling of connective tissue growth factor (CTGF).
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申请公布号 |
US7351407(B2) |
申请公布日期 |
2008.04.01 |
申请号 |
US20040510585 |
申请日期 |
2004.10.08 |
申请人 |
ALCON, INC. |
发明人 |
FLEENOR DEBRA L.;SHEPARD ALLAN;JACOBSON NASREEN;PANG IOK-HOU;CLARK ABBOT F. |
分类号 |
A61F9/007;A61K31/74;A61K31/00;A61K31/202;A61K31/404;A61K31/426;A61K31/427;A61K31/4439;A61K31/454;A61K31/519;A61K31/52;A61K45/00;A61P27/02;A61P27/06;C12N9/99 |
主分类号 |
A61F9/007 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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