发明名称 Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
摘要 The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/or signaling of connective tissue growth factor (CTGF).
申请公布号 US7351407(B2) 申请公布日期 2008.04.01
申请号 US20040510585 申请日期 2004.10.08
申请人 ALCON, INC. 发明人 FLEENOR DEBRA L.;SHEPARD ALLAN;JACOBSON NASREEN;PANG IOK-HOU;CLARK ABBOT F.
分类号 A61F9/007;A61K31/74;A61K31/00;A61K31/202;A61K31/404;A61K31/426;A61K31/427;A61K31/4439;A61K31/454;A61K31/519;A61K31/52;A61K45/00;A61P27/02;A61P27/06;C12N9/99 主分类号 A61F9/007
代理机构 代理人
主权项
地址