| 摘要 |
A method for treating sexual dysfunction is provided to treat male sexual dysfunction(MSD) and female sexual dysfunction(FSD) successfully by administering a specific carbamate compound alone or a combination of the compound with other drugs into a subject in need of the treatment. A method for treating sexual dysfunction comprises a step of administering a therapeutically effective amount of a compound represented by the formula(1) or a pharmaceutically acceptable salt thereof or an ester thereof into a subject in need of the treatment or administering a therapeutically effective amount of an enantiomer of the formula(1) substantially free of other enantiomers or an enantiomeric mixture wherein one enantiomer of the formula(1) predominates in a subject in need of the treatment, or a pharmaceutically acceptable salt thereof or an ester thereof. In the formula(1), R is H, C1-8 lower alkyl, halogen, C1-3 alkoxy, nitro, hydroxy, trifluoromethyl, and C1-3 thioalkoxy; x is an integer of 1 to 3 provided that R may be the same or different when x is 2 or 3; each R1 and R2 is independently selected from the group consisting of H, C1-8 lower alkyl, aryl, arylalkyl, C3-7 cycloalkyl; R1 and R2 may be joined to form a 5 to 7-membered heterocycle substituted by H, alkyl and aryl, wherein the cyclic compound may include 1 to 2 nitrogen atoms and 0 to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom. |
