| 摘要 |
Disclosed are pyrazolo[1,5-a]pyrimidines of formula I wherein the substituents are as defined in the specification. Compounds of the type disclosed are protein kinase inhibitors (for example MAPK/ERK and GSK3beta) useful in the treatment of diseases such as cancer, inflammation, arthritis, viral disease, neurodegenerative diseases, cardiovascular diseases and fungal diseases. |
| 申请人 |
SCHERING CORPORATION;PHARMACOPEIA, INC. |
发明人 |
GUZI, TIMOTHY J;PARUCH, KAMIL;DWYER, MICHAEL P;DOLL, RONALD J;GIRIJAVALLABHAN, VIYYOOR MOOPIL;MALLAMS, ALAN;ALVAREZ, CARMEN S;KEERTIKAR, KARTIK M;RIVERA, JOCELYN;CHAN, TIN-YAU;MADISON, VINCENT;FISCHMANN, THIERRY O;DILLARD, LAWRENCE W;TRAN, VINH D;HE, ZHEN MIN;JAMES, RAY ANTHONY;PARK, HAENGSOON;PARADKAR, VIDYADHAR M;HOBBS, DOUGLAS WALSH |
