发明名称 |
A synthetic heparin-binding growth factor analog |
摘要 |
Disclosed is synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a linker, which may be a hydrophobic linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.
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申请公布号 |
NZ538646(A) |
申请公布日期 |
2008.03.28 |
申请号 |
NZ20030538646 |
申请日期 |
2003.08.20 |
申请人 |
BIOSURFACE ENGINEERING TECHNOLOGIES INC |
发明人 |
PENA, LOUIS A;ZAMORA, PAUL O;LIN, XINHUA;GLASS, JOHN D |
分类号 |
A61K38/00;A61L27/34;C07H21/04;C07K14/50;(IPC1-7):C07K5/00;C07K5/02;C07K19/00;A61K38/16;A61K38/18;A61K39/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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