| 发明名称 |
Method for the Preparation of Oxime, Thiazolidine, Dithiane, Dithiolane, or Hydrazone Linked Analogues of Growth Hormone |
| 摘要 |
A method for the production of conjugated growth hormone is provided, wherein a GH derived aldehyde or ketone is reacted with an alkoxyamine, hydrazine or 2-aminothiol compound at acid pH in the presence of a dipolar solvent.
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| 申请公布号 |
US2008076700(A1) |
申请公布日期 |
2008.03.27 |
| 申请号 |
US20050577213 |
申请日期 |
2005.10.18 |
| 申请人 |
NOVO NORDISK A/S |
发明人 |
DORWALD FLORENCIO ZARAGOZA;SCHIODT CHRISTINE BRUUN |
| 分类号 |
A61K38/04 |
主分类号 |
A61K38/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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