Provided herein are benzoxazinone compounds of formula (I) and compositio ns containing the compounds. The compounds and compositions are useful in th e methods of inhibiting the action of serine hydrolase, including neutrophil elastase. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of serine hydrolase-mediated d iseases.
申请公布号
CA2664152(A1)
申请公布日期
2008.03.27
申请号
CA20072664152
申请日期
2007.09.20
申请人
KYORIN PHARMACEUTICAL CO., LTD.;ACTIVX BIOSCIENCES, INC.
发明人
HU, YI;KOHNO, YASUSHI;FRASER, ALLISTER;KOJIMA, AKIHIKO;ISHIYAMA, JUNICHI;SHREDER, KEVIN