| 发明名称 |
IN VIVO TRANSFORMATION OF PANCREATIC ACINAR CELLS INTO INSULIN-PRODUCING CELLS |
| 摘要 |
The present invention includes compositions and methods for transforming cells into glucose- responsive, insulin-production cells using a construct that expresses betacellulin and PDXl, e.g., transforming pancreatic acinar cells using one or more expression vectors that expressed betacellulin and PDXl using ultrasound targeted microbubble destruction (UTMD).
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| 申请公布号 |
CA2700360(A1) |
申请公布日期 |
2008.03.27 |
| 申请号 |
CA20072700360 |
申请日期 |
2007.09.21 |
| 申请人 |
BAYLOR RESEARCH INSTITUTE |
发明人 |
GRAYBURN, PAUL A.;CHEN, SHUYUAN |
| 分类号 |
A61K48/00;A61K38/17;A61K38/18;A61P3/10;C07H21/02;C07H21/04;C12N5/00;C12N5/02 |
主分类号 |
A61K48/00 |
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