发明名称 PYRAZOLOPYRIMIDINE DERIVATIVE
摘要 <p>[PROBLEMS] To provide a novel compound capable of inhibiting the activity of HSP90, particularly a novel compound capable of inhibiting the chaperon protein function of HSP90 and having an anti-tumor activity. [MEANS FOR SOLVING PROBLEMS] A pyrazolopyrimidine compound represented by the formula (1) having various substituents, which is capable of inhibiting the ATPase activity of HSP90 and has an anti-tumor activity; an HSP90 inhibitor comprising the compound represented by the formula (1); a pharmaceutical agent comprising the compound represented by the formula (1); an anti-cancer agent comprising the compound represented by the formula (1); a pharmaceutical composition comprising the compound represented by the formula (1); a method for the treatment of cancer by using the compound represented by the formula (1); and others. (1)</p>
申请公布号 WO2008035629(A1) 申请公布日期 2008.03.27
申请号 WO2007JP67933 申请日期 2007.09.14
申请人 DAIICHI SANKYO COMPANY, LIMITED;OHSUKI, SATORU;TENGEIJI, ATSUSHI;IKEDA, MASAHIRO;SHIBATA, YOSHIHIRO;NAGATA, CHIKAHIRO;SHIMADA, TAKASHI 发明人 OHSUKI, SATORU;TENGEIJI, ATSUSHI;IKEDA, MASAHIRO;SHIBATA, YOSHIHIRO;NAGATA, CHIKAHIRO;SHIMADA, TAKASHI
分类号 C07D495/16;A61K31/519;A61K31/5377;A61P35/00;A61P43/00;C07D495/22;C07D498/22;C07D519/00 主分类号 C07D495/16
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