Method for spatially high-resolution investigation of the structure of a sample marked with a fluorescent substance

摘要

The research process involves using a target protein (5) in living cells as the structure which is marked with the fluorescent substance (3). A ligand complex (1) including the fluorescent substance is bonded to and enzyme (4) by an enzymatic reaction in the cell. The enzyme is expelled as a fusion protein (6) together with the target protein.