| 发明名称 |
CLEAVAGE OF PRECURSORS OF INSULINS BY A VARIANT OF TRYPSIN. |
| 摘要 |
<p>The present invention relates to the production of a variant of recombinant trypsin with increased substrate specificity for arginine versus lysine in non-animal host organisms. Moreover, the present invention relates to a variant of recombinant trypsin and their production. Also provided are use of recombinant porcine pancreatic trypsin variants for cleavage of precursors of insulins, and kits containing the variant of trypsin.</p> |
| 申请公布号 |
MX2008003362(A) |
申请公布日期 |
2008.03.25 |
| 申请号 |
MX20080003362 |
申请日期 |
2006.08.26 |
| 申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
ERHARD KOPETZKI;FRANK ZOCHER;FRANK GEIPEL;STEPHAN GLASER;CHRISTOPH HOH;RAINER MUELLER |
| 分类号 |
C07K14/81 |
主分类号 |
C07K14/81 |
| 代理机构 |
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