发明名称 Phenylcarboxylate beta-secretase inhibitors for the treatment of alzheimer's disease
摘要 The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
申请公布号 US7348448(B2) 申请公布日期 2008.03.25
申请号 US20050562470 申请日期 2005.12.22
申请人 MERCK & CO., INC. 发明人 NANTERMET PHILIPPE G.;RAJAPAKSE HEMAKA ANTHONY;SELNICK HAROLD G.
分类号 C07C313/00;A61K;A61K31/18;A61K31/235;A61K31/24;A61K31/40;A61K31/445;C07C63/00;C07C233/66;C07C255/00;C07C255/57;C07C303/00;C07C311/08;C07D207/06;C07D207/08;C07D207/18;C07D211/06;C07D401/04 主分类号 C07C313/00
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