| 发明名称 |
POLYMER STABILIZED NEUROPEPTIDES |
| 摘要 |
A substantially hydrophilic conjugate is provided having a peptide that is capable of passing the blood-brain barrier covalently linked to a water-soluble nonpeptidic polymer such as polyethylene glycol. The conjugate exhibits improved solubility and in vivo stability and is capable of passing the blood-brain barrier of an animal.
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| 申请公布号 |
CA2385533(C) |
申请公布日期 |
2008.03.25 |
| 申请号 |
CA20002385533 |
申请日期 |
2000.10.04 |
| 申请人 |
SHEARWATER CORPORATION |
发明人 |
BENTLEY, MICHAEL DAVID;ROBERTS, MICHAEL JAMES |
| 分类号 |
A61K47/32;C07K14/665;A61K31/704;A61K38/00;A61K38/22;A61K47/48;A61K49/04;A61P25/04;C07K5/107;C07K7/06 |
主分类号 |
A61K47/32 |
| 代理机构 |
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代理人 |
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