发明名称 |
INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY |
摘要 |
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
|
申请公布号 |
US2008064718(A1) |
申请公布日期 |
2008.03.13 |
申请号 |
US20070689583 |
申请日期 |
2007.03.22 |
申请人 |
SAAVEDRA OSCAR M;CLARIDGE STEPHEN W;ZHAN LIJIE;RAEPPEL FRANCK;VAISBURG ARKADII;RAEPPEL STEPHANE;GAUDETTE FREDERIC;ISAKOVIC LJUBOMIR;GRANGER MARIE C;RAHIL JUBRAIL;MANNION MICHAEL;DEZIEL ROBERT |
发明人 |
SAAVEDRA OSCAR M.;CLARIDGE STEPHEN W.;ZHAN LIJIE;RAEPPEL FRANCK;VAISBURG ARKADII;RAEPPEL STEPHANE;GAUDETTE FREDERIC;ISAKOVIC LJUBOMIR;GRANGER MARIE C.;RAHIL JUBRAIL;MANNION MICHAEL;DEZIEL ROBERT |
分类号 |
A61K31/4365;A61P43/00;C07D495/04 |
主分类号 |
A61K31/4365 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|