发明名称 |
HIGHLY BIOAVAILABLE ORAL DELAYED RELEASE DOSAGE FORMS OF O-DESMETHYLVENLAFAXINE SUCCINATE. |
摘要 |
<p>An oral, highly bioavailable unit dosage form of O-desmethylvenlafaxine succinate (DVS) having a delayed release of at least about one hour and a sustained release over multiple hours to provide a total release of greater than about 85 % within about 12 to about 14 hours is described. In one embodiment, the superbioavailable DVS composition has a delayed release of about two hours and a total release of greater than about 95 % within about 12 to about 14 hours. Use of the formulation in treating depression and reducing the gastrointestinal side-effects of O-desmethylvenlafaxine (ODV) is also described.</p> |
申请公布号 |
MX2008000666(A) |
申请公布日期 |
2008.03.13 |
申请号 |
MX20080000666 |
申请日期 |
2006.07.13 |
申请人 |
WYETH. |
发明人 |
DIORIO, CHRISTOPHER RICHARD;SHAH, SYED M.;FAWZI, MAHDI B. |
分类号 |
A61K9/32;A61K9/50;A61K31/135 |
主分类号 |
A61K9/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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