ANALYTE DETECTION

摘要

A method of detecting an analyte in a sample, comprises the steps of: a) contacting the sample with a first ligand which binds specifically to the analyte and which is immobilised either on, or in the vicinity of, a sensor; b) prior to step (a) contacting the sample, or subsequent to step (a) contacting the immobilised analyte, with a material including a second ligand which binds specifically to the analyte, the material being activatable to form a polymerisation initiator; and c) activating the material; wherein the polymerisation initiator interacts with the sensor to change its physical properties, which causes a change in the optical or acoustic properties of the sensor.