PROCESS AND METHODS FOR THE PREPARATION OF OPTICALLY ACTIVE CIS-2-HYDROXYMETHYL-4-(CYTOSIN-1??-YL)-1,3-OXATHIOLANE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF.

摘要

There is provided a method for resolving a compound of formula (III), in the cis configuration: There is also provided a process for producing optically active compound of formula (I) or (II): wherein: R₁, R₂, R₃ are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.