DIPEPTIDYL PEPTIDASE IV INHIBITORS

摘要

Abstract The present invention relates to novel compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, their hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. The present invention more particularly provides novel compounds of the general formula (I). The compounds of the present invention are effective in lowering blood glucose, serum insulin, free fatty acids, cholesterol, triglyceride levels and useful in the treatment and/or prophylaxis of type II diabetes. These compounds are effective in the treatment of obesity, inflammation, autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.