摘要 |
The invention is a method for detecting a change in the conformational or energetic state of a molecular species, comprising the steps of: (i) immobilizing the molecular species, under conditions suitable for the reaction to occur; (ii) contacting at least part of the molecular species with a localized electromagnetic field; and (iii) detecting a change in dielectric constant during or after the reaction, to thereby detect a change in the conformational or energetic state of the molecular species. |