发明名称 |
STUDY, DETERMINATION OR EVALUATION METHOD |
摘要 |
<p>Disclosed is a method for the study, determination or evaluation of a pharmacological activity (e.g., an activity on fibromyalgia, an analgetic activity, an anti-stress activity) of a substance of interest by administering the substance to a SART-stressed animal and conducting the expression proteome analysis of a brain tissue of the animal. It becomes possible to search for a substance effective for fibromyalgia or a painful disease or an anti-stress substance by conducting the expression proteome analysis of a substance of interest with respect to how the substance affects the change in protein expression occurring in a brain tissue of a SART-stressed animal, or the like.</p> |
申请公布号 |
WO2008029836(A1) |
申请公布日期 |
2008.03.13 |
申请号 |
WO2007JP67291 |
申请日期 |
2007.09.05 |
申请人 |
ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE;NIPPON ZOKI PHARMACEUTICAL CO., LTD.;NISHIOKA, KUSUKI;KATO, TOMOHIRO;FUJISAWA, HIROKI |
发明人 |
NISHIOKA, KUSUKI;KATO, TOMOHIRO;FUJISAWA, HIROKI |
分类号 |
C12Q1/02;A61K35/36;A61K45/00;A61P25/04;A61P25/18;G01N21/64;G01N27/447 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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