摘要 |
There is provided the use of WNT5A, or a therapeutically effective fragment or derivative thereof, in the preparation of a medicament for use in the prevention, reduction or inhibition of scarring. There is also provided the use of WNT5A, or a therapeutically effective fragment or derivative thereof, in the preparation of a medicament for use in the prevention and/or treatment of a fibrotic disorder. Further aspects relate to methods by which scarring may be prevented, reduced or inhibited, and by which fibrotic disorders may be prevented and/or treated. Therapeutically effective amounts of WNT5A, or its fragments or derivatives, that may be used in the medicaments or methods of the invention are also provided. |
申请人 |
RENOVO LIMITED;FERGUSON, MARK, WILLIAM, JAMES;LAVERTY, HUGH, GERARD;OCCLESTON, NICHOLAS;O'KANE, SHARON;NIELD, KERRY;GOLDSPINK, NICHOLAS |
发明人 |
FERGUSON, MARK, WILLIAM, JAMES;LAVERTY, HUGH, GERARD;OCCLESTON, NICHOLAS;O'KANE, SHARON;NIELD, KERRY;GOLDSPINK, NICHOLAS |