MEDICINAL COMPOSITION FOR PREVENTION OF TRANSITION TO OPERATIVE TREATMENT FOR PROSTATIC HYPERTROPHY

摘要

The present invention provides an agent useful for the prevention of transition to surgical therapy for benign prostatic hyperplasia and the like. The present invention relates to a pharmaceutical composition for the prevention of transition to surgical therapy for benign prostatic hyperplasia, which comprises an indoline derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof (in the formula, R represents an optionally substituted aliphatic acyl group, a hydroxyalkyl group, an aliphatic acyloxyalkyl group, a substituted lower alkyl group, an optionally substituted aromatic acyl group, a furoyl group, a pyridylcarbonyl group or the like; R 1 represents a cyano group or a carbamoyl group; and R 2 represents an optionally substituted lower alkyl group).