| 发明名称 |
Method of modulating the profileration of medullary thyroid carcinoma cells |
| 摘要 |
<p>The present invention is directed to a compound of the formula:
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ cyclo[Tic-Tyr-D-Trp-Lys-Abu-Phe];
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ D-Nal-cyclo[Cys-Tyr-D-Trp-Lys-Val-Cys]-Thr-NH 2 ;
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ 4-(2-Hydroxyethyl)-1-piperazinylacetyl-D-Phe-cyclo(Cys-Tyr-D-Trp-Lys-Abu-Cys)-Thr-NH 2 ; and
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ 4-(2-Hydroxyethyl)-1-piperazine-2-ethanesulfonyl-D-Phe-cyclo(Cys-Tyr-D-Trp-Lys-Abu-Cys)-Thr-NH 2 ,</p> |
| 申请公布号 |
EP1897889(A2) |
申请公布日期 |
2008.03.12 |
| 申请号 |
EP20070006462 |
申请日期 |
2002.03.06 |
| 申请人 |
UNIVERSITA' DEGLI STUDI DI FERRARA;IPSEN PHARMA |
发明人 |
DEGLI UBERTI, ETTORE CIRO;CULLER, MICHAEL DEWITT;ZATELLI, MARIA CHIARA;COY, DAVID H. |
| 分类号 |
C07K14/655;G01N33/48;A61K38/00;A61K38/08;A61K38/31;A61K45/00;A61K51/00;A61P35/00;A61P35/04;A61P43/00;C07K7/06;C07K7/64;C12N5/06;C12Q1/02;G01N33/68 |
主分类号 |
C07K14/655 |
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