发明名称 |
Means for increasing intracellular levels of protoporphyrin IX and use thereof |
摘要 |
<p>The present invention is related to a nucleic acid molecule comprising a double-stranded structure, whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and the first stretch is at least partially complementary to a target nucleic acid, and whereby the second strand comprises a second stretch of contiguous nucleotides and whereby said second stretch is at least partially complementary to the first stretch, whereby the first stretch comprises a nucleic acid sequence which is complementary to a nucleotide sequence starting from position 383, 1013 or 1982 of the nucleic acid according to SEQ.ID.No. 1.</p> |
申请公布号 |
EP1897941(A1) |
申请公布日期 |
2008.03.12 |
申请号 |
EP20060018993 |
申请日期 |
2006.09.11 |
申请人 |
MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN;CHARITE-UNIVERSITAETSMEDIZIN BERLIN |
发明人 |
KEMMNER, WOLFGANG;MOESTA, THOMAS;SCHLAG, PETER-MICHAEL |
分类号 |
A61K31/713;A61P35/00;C12N15/113 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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