发明名称 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES FOR USE IN MEDICAL IMAGING
摘要 <p>The invention provides a compound of formula (I); or a salt or solvate thereof, wherein: R1 is hydrogen or C1-4 alkyl; R2 and R4 are each independently selected from C1-4 alkyl, [11C]C1-4 alkyl, and [18F]&mdash;C1-4 fluoroalkyl provided that at least one of R2 and R4 is [11C]C1-4 alkyl or [18F]&mdash;C1-4 fluoroalkyl; and R3 is halo. Such compounds having use for imaging central nervous system receptors.</p>
申请公布号 EP1896400(A1) 申请公布日期 2008.03.12
申请号 EP20060755605 申请日期 2006.06.23
申请人 HAMMERSMITH IMANET, LTD 发明人 ROBINS, EDWARD GEORGE;ARSTAD, ERIK
分类号 C07B59/00;C07C323/44 主分类号 C07B59/00
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