Sustained release coating for medical devices

摘要

There is provided a medical device chosen from sutures, surgical staples, implants and catheters adapted for insertion into a human or animal body, characterised in that its exterior surface is coated with
<Italic>i)</Italic> an inner first layer of a biocompatible carrier providing sustained release of a biologically active agent dissolved or dispersed therein;
<Italic>ii)</Italic> an outer second layer consisting of a film of said biologically active agent applied on said inner first layer, where said film optionally may contain at least one non-polymeric adjuvant, diluent or carrier.

The present medical device is especially well suited for treatment or prevention of restenosis and disorders related thereto.