LIPOSOMES CONTAINING MULTIPLE BRANCH PEPTIDE CONSTRUCTIONS FOR USE AGAINST HUMAN IMMUNODEFICIENCY VIRUS

摘要

The incorporation of multiple branch peptide constructions having activity against HIV (such as those described in WO 95/07929 and WO 98/29443) into liposomes of sufficient size for white blood cell internalisation (e.g. greater than 150 nm and preferably approximately 250 to 400 nm) has been shown to increase the activity of those MBPCs manifold. The liposomes and pharmaceutical compositions containing them are claimed.