发明名称 COMPOSITION OF LABDANE DITERPENES EXTRACTED FROM ANDROGRAPHIS PANICULATA.
摘要 <p>Composition characterized for being constituted of molecules identified as diterpenic labdanes that are obtained from a valuable plant species from Andrographis paniculata, dried herb by a special process of extraction, for the treatment of autoimmune other immunological diseases in human's beings and animals, exhibiting a low toxicity and absence of significant side effects. Likewise, the new composition is useful for preparing a pharmaceutical composition useful for preventing and treating Alzheimer's disease. The composition inhibits the synthesis of pro-inflammatory cytokines, as a result of activating the PPAR gamma receptor and diminishing the nuclear factor kappa B. In addition, to its own therapeutic features, this new composition solves the inconveniences of the current products, medicines and procedures, that have an important toxicity level and/or cause non desired side effects. The present invention has applications in immunopharmacology, clinical and pre clinical human and veterinary pharmacology, pharmaceutical technology, rheumatology, and clinical immunology, immunotherapy, organ and tissue transplantation, and the immunodefficiency diseases as AIDS.</p>
申请公布号 MXPA06008738(A) 申请公布日期 2008.03.07
申请号 MX2006PA08738 申请日期 2004.05.21
申请人 UNIVERSIDAD AUSTRAL DE CHILE 发明人 JUAN LUIS HANCKE OROZCO;RAFAEL AGUSTIN BURGOS AGUILERA
分类号 A61K36/19;A61P37/00 主分类号 A61K36/19
代理机构 代理人
主权项
地址