A novel crystalline anhydrate of the free acid and a crystalline anhydrous besylate salt of a selective PPAR gamma partial agonist which has a fused bicyclic aromatic group attached to an oxypropanoic acid moiety are stable and non-hygroscopic. The compounds are suitable for preparing pharmaceutical formulations for the treatment of type 2 diabetes, hyperglycemia, obesity, and dyslipidemia.
申请公布号
WO2007103252(A3)
申请公布日期
2008.03.06
申请号
WO2007US05493
申请日期
2007.03.02
申请人
MERCK & CO., INC.;SONG, ZHIGUO, J.;MCKEOWN, ARLENE, E.