摘要 |
<p>Disclosed is a method for producing a compound represented by the formula (I) below, which is characterized in that a compound represented by the formula (II) below or a salt thereof is reacted with a compound represented by the formula (III) below in the presence of a condensing agent. (II) [In the formula, R<SUP>1</SUP> represents (1) an optionally substituted acetidin-1-yl group, (2) an optionally substituted pyrrolidin-1-yl group, (3) an optionally substituted piperidin-1-yl group or the like; and R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP> and R<SUP>5</SUP> may be the same or different and represent a hydrogen atom or afluorine atom.] (III) [In the formula, R<SUP>6</SUP> represents a hydrogen atom or a fluorine atom.] (I) [In the formula, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP> and R<SUP>6</SUP> are as defined above.]</p> |
申请人 |
EISAI R & D MANAGEMENT CO., LTD.;NAGAI, MITSUO;MATSUSHIMA, TOMOHIRO;KAMADA, ATSUSHI;WAKASUGI, KAZUNORI;SHIROTORI, SHUJI;ABE, SHINYA;NARA, KAZUMASA;SAKAGUCHI, TAKAHISA |
发明人 |
NAGAI, MITSUO;MATSUSHIMA, TOMOHIRO;KAMADA, ATSUSHI;WAKASUGI, KAZUNORI;SHIROTORI, SHUJI;ABE, SHINYA;NARA, KAZUMASA;SAKAGUCHI, TAKAHISA |