ORAL MICROPARTICULATE, ANTI-MISUSE DRUG FORMULATION

摘要

The invention concerns solid microparticulate analgesic oral drugs. The invention aims at providing novel analgesic drugs for preventing misuse and addiction to certain analgesics and/or controlling variability of plasma concentration and/or facilitating oral administration, and/or combining together analgesics and/or with one or more active principles in a common oral formulation. The inventive drug comprises (i) anti-misuse means and a plurality of analgesic modified release microcapsules of average diameter ranging between 50 and 600 µm, (ii) at least 100 microcapsules per dose; said drug capable of being administered once or twice a day for analgesic purposes.