摘要 |
The invention relates to derivatives having general formula (I), in which: X represents an optionally substituted phenyl group; R<SUB>1 </SUB>represents a hydrogen atom, a halogen, an optionally substituted (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy group, an optionally substituted (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group, a (C<SUB>3</SUB>-C<SUB>7</SUB>)cycloalkyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group, a (C<SUB>3</SUB>-C<SUB>7</SUB>)cycloalkyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy group, a hydroxy, an amino; R<SUB>2</SUB> represents a hydrogen atom, an optionally substituted (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group, an optionally substituted (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy group, a (C<SUB>3</SUB>-C<SUB>7</SUB>)cycloalkyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl group, a (C<SUB>3</SUB>-C<SUB>7</SUB>)cycloalkyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy group, a (C<SUB>2</SUB>-C<SUB>6</SUB>)alkenyl group, a (C<SUB>2</SUB>-C<SUB>6</SUB>)alkynyl group, a -CO-R<SUB>5</SUB> group, a -CO-NR<SUB>6</SUB>R<SUB>7</SUB> group, a -CO-O-R<SUB>8 </SUB>group, a -NR<SUB>9</SUB>-CO-R<SUB>10</SUB> group, a -NR<SUB>11</SUB>R<SUB>12 </SUB>group, a halogen atom, a cyano group or an optionally substituted phenyl group; R<SUB>3 </SUB>represents a hydrogen atom, a (C<SUB>1</SUB>- C<SUB>6</SUB>)alkyl group or a halogen atom; and R<SUB>4</SUB> represents a hydrogen atom or a halogen atom, said derivatives taking the form of a base or an acid addition salt. The invention also relates to the preparation method thereof and to the use of same in therapeutics. |