发明名称 DI-AMINO-SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE
摘要 The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various fibrotic and mast cell related diseases such as mastocytosis. The compounds have a general Formula (I) wherein R<SUP>1-6</SUP>, X and Y are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.
申请公布号 WO2008011110(A3) 申请公布日期 2008.03.06
申请号 WO2007US16383 申请日期 2007.07.17
申请人 AMGEN INC.;CHEN, NING;HU, ESSA 发明人 CHEN, NING;HU, ESSA
分类号 C07D261/20;A61K31/422;A61P37/00;C07D413/12;C07D413/14;C07D498/04 主分类号 C07D261/20
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