PRION PROCESSING

摘要

A method for processing prions is disclosed, comprising contacting at least one porous medium with a pathogenic prion-containing fluid such that pathogenic prions are retained and/or captured by the porous medium; contacting the porous medium with another fluid such that pathogenic prions are released from the porous medium to provide a first released pathogenic prion-containing fluid; placing a fluid containing the released pathogenic prions in a first spin device including a separation medium; and, centrifuging the spin device to provide a first concentrated pathogenic prion-containing retentate.