SYSTEMS AND METHODS FOR CORRECTING FOR UNEQUAL ION DISTRIBUTION ACROSS A MULTI-CHANNEL TOF DETECTOR

摘要

Systems and methods for calculating ion flux. In one embodiment, a mass s pectrometer includes an ion source for emitting a beam of ions from a sample and at least one detector positioned downstream of said ion source. The at least one detector comprises a plurality of detector channels. The mass spec trometer also includes a controller operatively coupled to the plurality of detector channels. The controller is configured to: determine ion abundance data correlated to each detector channel; determine corrected ion abundance data correlated to each detector channel; determine confidence data correspo nding to the ion abundance data for each of the detector channels; and deter mine a confidence weighted abundance estimate of the ion flux correlated to both the ion abundance data and to the confidence data.