发明名称 |
METHOD FOR CONTROL OF DRUG ELUTION RATE AND COMPOSITION FOR COATING OF DRUG-ELUTING STENT |
摘要 |
<p>Disclosed are a method for controlling the elution of a drug from a stent and a drug-eluting stent capable of reducing the restenosis rate after therapy. A coating composition for a drug-eluting stent comprising an endothelin receptor antagonist and a copolymer of 2-methacrylcyloxyethyl phosphorylcholine and n-butyl methacrylate. The elution of the endothelin receptor antagonist from the coating composition can be controlled by varying the ratio of 2-methacryloyloxyethyl phosphorylcholine to n-butyl methacrylate in the copolymer.</p> |
申请公布号 |
EP1894582(A1) |
申请公布日期 |
2008.03.05 |
申请号 |
EP20060745959 |
申请日期 |
2006.05.01 |
申请人 |
TOKYO MEDICAL AND DENTAL UNIVERSITY |
发明人 |
AZUMA, H.;NIIMI, Y.;IWASAKI, Y.;NAKABAYASHI, N. |
分类号 |
A61L31/00;A61K31/506;A61K47/32;A61P9/02;A61P9/12 |
主分类号 |
A61L31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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