Methods for treating inflammatory conditions or inhibiting JNK using pyrazoloanthrone derivatives

摘要

Disclosed is the use of a compound of formula I or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are absent or present and are as defined in the specification, in the manufacture of a medicament for treating or preventing Type II diabetes, obesity, Type I diabetes, diabetes insipidus, diabetes mellitus, maturity-onset diabetes, juvenile diabetes, insulin-dependant diabetes, non-insulin dependant diabetes, malnutrition-related diabetes, ketosis-prone diabetes, ketosis-resistant diabetes, otitis extema, acute otitis media, hearing loss, systemic lupus erythematosus, pancreatitis, peritonitis, sepsis, alcohol or toxin-induced liver disease, sclerosis, steatosis, ischemia-reperfusion injury, allergic rhinitis, an allergy, nephropathy, acute respiratory distress syndrome, chronic obstructive pulmonary disease, pulmonary interstitial fibrosis, liver fibrosis, renal fibrosis, or fibrosis associated with wound healing or burn-healing.