| 发明名称 |
CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH |
| 摘要 |
<p>Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.</p> |
| 申请公布号 |
SI1509537(T1) |
申请公布日期 |
2008.02.29 |
| 申请号 |
SI20030030953T |
申请日期 |
2003.04.25 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
ARIMILLI MURTY N.;BECKER MARK W.;BRYANT CLIFFORD;CHEN JAMES M.;CHEN XIAOWU;DASTGAH AZAR;FARDIS MARIA;HE GONG-XIN;JIN HAOLUN;KIM CHOUNG U.;LEE WILLIAM A.;LEE CHRISTOPHER P.;LIN KUEI-YING;LIU HONGTAO;MACKMAN RICHARD L.;MITCHELL MICHAEL L.;NELSON PETER H.;PYUN HYUNG-JUNG;ROWE TANISHA D.;SWAMINATHAN SUNDARAMOORTHI;TARIO JAMES D.;ZHANG LIJUN;SPARACINO MARK;WANG JIANYING;WILLIAMS MATTHEW A.;XU LIANHONG;YANG ZHENG-YU;YU RICHARD H.;ZHANG JIANCUN |
| 分类号 |
C12N9/99;A61K31/4155;A61K31/66;A61K31/665;A61K31/675;A61P31/18;A61P43/00;C07D213/75;C07D213/85;C07D231/12;C07D231/20;C07D233/42;C07D239/48;C07D239/80;C07D243/04;C07D265/18;C07D307/68;C07D401/06;C07D403/06;C07D471/14;C07D491/04;C07F;C07F9/02;C07F9/38;C07F9/40;C07F9/44;C07F9/58;C07F9/62;C07F9/645;C07F9/6506;C07F9/6509;C07F9/6512;C07F9/653;C07F9/6533;C07F9/655;C07F9/6558;C07F9/6561;C07F9/6584;C12N9/16;C12Q1/18;C12Q1/37;C12Q1/44;C12Q1/70;G01N33/04;G01N33/50 |
主分类号 |
C12N9/99 |
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