摘要 |
<p>The invention relates to a Mannich reaction at accelerated pressure for the direct preparation of N -monosubstituted ²-keto amines of formula
and its addition salts of proton acids, wherein R 1 and R 2 independently represent alkyl, cycloalkyl, aryl or aralkyl, each being optionally further substituted with alkyl, alkoxy and/or halogen via wherein R 1 and R 2 are as defined above.</p> |