发明名称 |
Crystalline polymorphs of a CXC-chemokine receptor ligand |
摘要 |
The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure: These four polymorphic forms, herein referred to as Forms I, II, III and IV are active as a CXC-chemokine receptor ligands. The invention is further directed to formulations, methods of treatment, and processes of synthesis of these polymorphic forms. |
申请公布号 |
ZA200606295(B) |
申请公布日期 |
2008.02.27 |
申请号 |
ZA20060006295 |
申请日期 |
2006.07.28 |
申请人 |
SCHERING CORPORATION |
发明人 |
HU, MENGWEI;DWYER, MICHAEL;KIM-MEADE, AGNES;FU, XIAOYONG;ZHANG, SHUYI;YU, YOUNONG;TAVERAS, ARTHUR G.;YIN, JIANGUO;MCALLISTER, TIMOTHY;KLOPPER, KEVIN |
分类号 |
A61K;A61K31/34;A61K31/341;A61P;C07D;C07D307/52 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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