发明名称 1-Benzyl-5-piperazin-1-yl-3,4 dihydro-1H-quinazolin-2-one derivatives and the respective 1H-benzo(1,2,6)thiadiazine-2,2-dioxide and 1,4-dihydro-benzo(D) (1,3)oxazin-2-one derivatives as modulators of the 5-hydroxytryptamine receptor (5-HT) for the treatment of diseases of the central nervous system
摘要 The invention provides compounds of the formula I: and pharmaceutically acceptable salts or prodrugs thereof, wherein m, n, p, q, X, Y, Z, A, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>9 </SUP>and R<SUP>10 </SUP>are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula I.
申请公布号 ZA200605434(B) 申请公布日期 2008.02.27
申请号 ZA20060005434 申请日期 2006.06.30
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 SUI, MENG;ZHAO, SHU-HAI
分类号 A61K;A61K31/517;A61K31/536;A61K31/5415;A61K31/549;A61P;C07D;C07D239/80;C07D265/18;C07D285/16;C07D405/06;C07D413/02;C07D417/02 主分类号 A61K
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