| 摘要 |
FIELD: medicine. ^ SUBSTANCE: the present innovation refers to new mutations, mutation combinations or those of mutation profiles of the genes of reverse transcriptase HIV-1 and/or protease that correlate with phenotypic resistance to medicinal preparations against HIV. To be more concrete, the present innovation deals with applying genotypic characteristics of HIV target population and subsequent correlation of the present information at phenotypic interpretation to establish the correlation of viral mutation profiles at resistance to medicinal preparations. The innovation in question enables to apply the data obtained in screening medicinal preparations applied against HIV-infection. ^ EFFECT: higher efficiency. ^ 12 cl, 2 dwg, 14 ex, 13 tbl |
