摘要 |
The present invention relates to novel compounds having a function of a peptide in the amylin family, related nucleic acids, expression constructs, host cells, and processes production of the compounds. The compounds of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent metabolic disorders such as obesity, diabetes, and increased cardiovascular risk. |
申请人 |
AMYLIN PHARMACEUTICALS, INC. |
发明人 |
SOARES, CHRISTOPHER J.;HANLEY, MICHAEL R.;LEWIS, DIANA YVONNE;PARKES, DAVID GEOFFREY;JODKA, CAROLYN MARIE;PRICKETT, KATHRYN S.;GHOSH, SOUMITRA, MACK;CHRISTINE MARIE;LIN, QING |