| 发明名称 |
P4HAS AS MODIFIERS OF THE IGFR PATHWAY AND METHODS OF USE |
| 摘要 |
<p>Human PFK genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of PFK are provided.</p> |
| 申请公布号 |
EP1759207(A4) |
申请公布日期 |
2008.02.27 |
| 申请号 |
EP20050766099 |
申请日期 |
2005.06.20 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
FRIEDMAN, LORI S.;FRANCIS-LANG, HELEN;PARKS, ANNETTE L.;SHAW, KENNETH JAMES;HEUER, TIMOTHY S.;BJERKE, LYNN MARGARET |
| 分类号 |
G01N33/53;C07K5/00;C07K14/00;C12Q1/26 |
主分类号 |
G01N33/53 |
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